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Imiquimod is a new type of medication called an immune response modifier. Imiquimod works by stimulating the immune system to release a number of chemicals called cytokines, which are important in fighting viruses and destroying cancer cells.

When used to treat skin cancers and pre-cancerous lesions it results in inflammation, which destroys the lesion. It is particularly useful on areas where surgery or other treatments may be difficult, complicated or otherwise undesirable, especially the face and lower legs. Imiquimod is currently being used to treat various types of genital warts. Although it is recommended that you use this product with caution, as it does tend to burn and irritate the skin.

A course of treatment ranges from 4 to 16 weeks. Before starting, a biopsy may be performed to confirm the diagnosis. Your doctor should carefully monitor the treatment because you may need to apply the cream more or less frequently than originally planned or for a shorter or longer course, depending on response. Once the inflammation has settled there is generally a good or excellent cosmetic result with little scarring.

Areas treated with Imiquimod will be come inflamed. The effects include itching, burning, redness, ulceration (sores), scabbing, flaking and pain. These reactions indicate that the cream is likely to be effective - if there is no inflammation, Imiquimod is unlikely to clear the lesions. An exaggerated response may clear the lesions sooner than expected - sometimes after as few as three or four applications. In some patients, surrounding untreated areas also become inflamed but this will settle when treatment is discontinued.

If you develop a severe reaction with black scabs and ulceration, stop applying the cream and arrange to see your doctor as soon as possible.

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